Course detail

Advanced Light Microscopy - Imaging Theory

FSI-9MIA Acad. year: 2022/2023 Summer semester

The course explains principles of light microscopy of three-dimensional objects in terms of wave optics. Image properties are described using the formalism of 3D pupil and transfer functions. Properties of advanced microscopic techniques for 3D imaging are explained, especially those of confocal microscopy and coherence-controlled holographic microscopy.

Language of instruction

Czech

Learning outcomes of the course unit

Knowledge of fundamentals of theoretical description of microscope imaging of 3D objects of their relation to experiment and competence to apply them in practice.

Prerequisites

Wave and Fourier optics, geometrical optics, fundamentals of light microscopy.

Planned learning activities and teaching methods

The course is taught through lectures explaining the basic principles and theory of the discipline. The lecture is completed by advanced optical demonstrations and experiments with light microscopes.

Assesment methods and criteria linked to learning outcomes

Examination is oral. Detailed knowledge of explained matter is proved. Examined student can use a literature.

Aims

Understanding of principles of 3D light microscopy and microscopic imaging.
Acquiring of methods for fundamental 3D imaging characteristics calculation.

Specification of controlled education, way of implementation and compensation for absences

Presence at lectures is not obligatory, but recommended.

The study programmes with the given course

Programme D-FIN-P: Physical Engineering and Nanotechnology, Doctoral, recommended course

Programme D-FIN-K: Physical Engineering and Nanotechnology, Doctoral, recommended course

Type of course unit

 

Lecture

20 hours, optionally

Syllabus

1. Important knowledge in the field of light microscopy and wave optics
2. Light wave interaction with an object
3. Imaging from the point of view of wave optics
4. Imaging by confocal micorscope
5. Imaging by interference and holographic microscope
6. Imaging by fluorescence microscope
7. Imaging in bright field
8. Another specific cases of imaging