The research focuses on the internal directional arrangement of the tissue structures and their influence on the mechanical properties and behavior of tissues, both soft (arterial, vocal cords) and hard (bone tissue) ones. Analyses are performed using various imaging techniques (Computed Tomography, micro-CT, polarizing microscopy, confocal or multifocal microscopy, holographic microscopy) at different levels of modeling. Constitutive models of inhomogeneous and anisotropic (among others) tissue properties are used for computational modelling in biomechanics, and knowledge of tissue structure is essential for development of these models. Parameters of constitutive models are determined from mechanical tests and from information about the tissue structure.

Awards and further information

Award of prof. Jaroslav Buchar (SVS FEM): 2021 1. place – Ing. Lucie Orlova (only in Czech)

Project Brno Ph.D. talent 2021 – Ing. Anna Hrubanová

Award of prof. Babušky 2018 – Ing. Ondřej Lisický (only in Czech)

Laboratory of Biomechanics

Web pages

Projects

MR1323S01000 Use of computer modeling and 3D printing for anesthesiologic management in pediatric patient with orofacial cleft malformation

22-14387J Design and manufacturing of 4D metamaterials based on printed structures with embedded elements of smart materials

21-21935S Computational modelling of pulsatile flow in compliant tubes with application for tandem carotid stenosis

CZ.02.01.01/00/22_008/0004634 MEBioSys – Mechanical Engineering of Biological and Bio-inspired Systems (funded by Ministry of Education, Youth and Sports)

Significant publications

FISCHER, J.; HEIDROVÁ, A.; HERMANOVÁ, M.; BEDNAŘÍK, Z.; JOUKAL, M.; BURŠA, J. Structural parameters defining distribution of collagen fiber directions in human carotid arteries. Journal of the mechanical behavior of biomedical materials, 2024, roč. 153, č. 5, s. 106494. ISSN: 1751-6161.

SKÁCEL, P.; BURŠA, J. Need for transverse strain data for fitting constitutive models of arterial tissue to uniaxial tests. Journal of the mechanical behavior of biomedical materials, 2024, roč. 150, č. 150, s. 106194. ISSN: 1751-6161.

APOSTOLOPOULOS, V.; BOHÁČ, P.; MARCIÁN, P.; STANICZKOVA ZAMBO, I.; PAZOUREK, L.; MAHDAL, M.; NERADIL, J.; NÁVRAT, T.; TOMÁŠ, T. Micro-CT, Mechanical, and Histological Examination of the Effect of Local Adjuvants on Porcine Cortical Bone Following Intralesional Curettage of Bone Tumors. ANNALS OF SURGICAL ONCOLOGY, 2024, roč. 31, č. 2024, s. 6282-6290. ISSN: 1068-9265.

Contact person
prof. Ing. Jiří Burša, Ph.D.