Prediction of mechanical behaviour and assessment of limit states of organs of a specific patient using computational and experimental modelling is applied in planning operations and design of individualised implants or medical products. In implant design, the application of metamaterials, specifically auxetic materials, is currently being explored, which, due to their unique mechanical properties, offer new opportunities for improving the functionality and integration of implants with biological tissue. Various imaging techniques (CT, MRI) are used to create individualized (geometric, constitutive, etc.) models, which can provide a plethora of valuable in vivo data for a specific patient. The created partial geometry models are also used for 3D printing not only of the tissue structures themselves, but also of individualized implants and devices. We also model a fluid-structure-acoustic interaction between the compliant vocal folds and airflow and acoustics of the vocal tract as well as the upper airway patency using CFD analyses. We use an individualized approach combined with similar methods in the design of an extracorporeal circulation peristaltic pump.

Awards and further information

Award of prof. Jaroslav Buchar (SVS FEM):

• 2019 – 2. place – Ing. Ondřej Mach

• 2024 – 2. place – Ing. Lukáš Janáčik

Prof. Valenta and prof. Čiháka prize for the best diploma and dissertation thesis:

• 2012 – the best diploma thesis – Ing. Jan Kohoutek
• 2014 – the best diploma thesis – Ing. Eva Prášilová
• 2016 – the best dissertation thesis – Ing. Jiří Valášek

Gunnar Rugheimer’s Prize

• 2017 – the best poster on the PEVoC 2017 – Ing. Petr Hájek

Laboratory of Biomechanics

Web pages

Projects

MR1323S01000 Use of computer modeling and 3D printing for anesthesiologic management in pediatric patient with orofacial cleft malformation

22-14387J Design and manufacturing of 4D metamaterials based on printed structures with embedded elements of smart materials

21-21935S Computational modelling of pulsatile flow in compliant tubes with application for tandem carotid stenosis

CZ.02.01.01/00/22_008/0004634 MEBioSys – Mechanical Engineering of Biological and Bio-inspired Systems (funded by Ministry of Education, Youth and Sports)

Significant publications

JAGOŠ, J.; KOHÚT, J.; NOVOTNÝ, T.; KŘIVKA, T.; HÁJEK, P.; FORMÁNEK, M.; LISICKÝ, O.; BURŠA, J. In silico hemodynamical simulations show additional benefits of artery wall softening induced by antihypertensive drugs. COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2024, roč. 245, s. 108016. ISSN: 1872-7565. (odkaz)

THOMKOVÁ, B.; MARCIÁN, P.; BORÁK, L.; JOUKAL, M.; WOLFF, J. Biomechanical performance of dental implants inserted in different mandible locations and at different angles: A finite element study. JOURNAL OF PROSTHETIC DENTISTRY, 2024, roč. 131, č. 1, s. 128. ISSN: 0022-3913. (odkaz)

APOSTOLOPOULOS, V.; BOHÁČ, P.; MARCIÁN, P.; NACHTNEBL, L.; MAHDAL, M.; PAZOUREK, L.; TOMÁŠ, T. Biomechanical comparison of all-polyethylene total knee replacement and its metal-backed equivalent on periprosthetic tibia using the finite element method. Journal of Orthopaedic Surgery and Research, 2024, roč. 19, č. 1, s. 153 ( s.)ISSN: 1749-799X.

Contact person
Ing. Petr Marcián, Ph.D.