viz angl.

Arrangement for production of hyperpolarized xenon

conference paper

en

The rapidly growing interest in production of hyperpolarized noble gasses (HpG), predominantly 3He and 129Xe for Nuclear Magnetic Resonance (NMR) experiments is driven by potentially attractive medical applications. Neither helium nor xenon is normally present in the body, so the experiments do not suffer from unwanted background signals. Among the potential medicine applications, the opportunity to image organs with low water content and/or with air spaces, such as colon or lungs, has raised a considerable interest. Current conventional imaging techniques cannot provide good images of these hollow spaces, and not even of the surrounding tissues. These applications show that HpG may become a useful tool for non-invasive investigation of human lung ventilation, giving access to static imaging during breathhold, dynamics of inspiration/expiration, and functional imaging. One of the two techniques and the more promising one of achieving the hyperpolarized state of noble gasses is based on the spin-exchange collision between atoms of Rb and 129Xe. This paper describe the way of optical pumping of Rb vapour by Ti:Sa laser which is necessary for attainment hyperpolarized state of 129Xe.

viz. anglická anotace

The rapidly growing interest in production of hyperpolarized noble gasses (HpG), predominantly 3He and 129Xe for Nuclear Magnetic Resonance (NMR) experiments is driven by potentially attractive medical applications. Neither helium nor xenon is normally present in the body, so the experiments do not suffer from unwanted background signals. Among the potential medicine applications, the opportunity to image organs with low water content and/or with air spaces, such as colon or lungs, has raised a considerable interest. Current conventional imaging techniques cannot provide good images of these hollow spaces, and not even of the surrounding tissues. These applications show that HpG may become a useful tool for non-invasive investigation of human lung ventilation, giving access to static imaging during breathhold, dynamics of inspiration/expiration, and functional imaging. One of the two techniques and the more promising one of achieving the hyperpolarized state of noble gasses is based on the spin-exchange collision between atoms of Rb and 129Xe. This paper describe the way of optical pumping of Rb vapour by Ti:Sa laser which is necessary for attainment hyperpolarized state of 129Xe.

xenon, hyperpolarization, Ti:Sa laser

26.05.2005

80-214-2942-9

Proceedings of the International Interdisciplinary HONEYWELL EMI 2005

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