Experimental and computational modelling of the flow of inhaled fibrous particles in human airways

abstract

en

The complex nature of the flow of inhaled fibres poses a persistent challenge in accurately modelling and calculating fibre flow and deposition in human airways. Computational limitations and a lack of experimental data for validation continue to restrict progress in this field. To address this challenge, our work integrates computational modelling and experimental measurements. The computational simulations were performed using the Euler-Lagrange Euler-Rotation (ELER) approach. To assess its suitability for modelling respiratory fibre transport and deposition, the simulation of particle behaviour was compared to our experimental data on fibre orientation during steady flow.

The complex nature of the flow of inhaled fibres poses a persistent challenge in accurately modelling and calculating fibre flow and deposition in human airways. Computational limitations and a lack of experimental data for validation continue to restrict progress in this field. To address this challenge, our work integrates computational modelling and experimental measurements. The computational simulations were performed using the Euler-Lagrange Euler-Rotation (ELER) approach. To assess its suitability for modelling respiratory fibre transport and deposition, the simulation of particle behaviour was compared to our experimental data on fibre orientation during steady flow.

Euler-Lagrange Euler-Rotation; fibers; fibres; inhalation; human airways

25.08.2024

Finish Association for Aerosol Research

Tampere

Abstract Book of European Aerosol Conference 2024 (EAC2024), 25.8. – 30.8.2024, Tampere, Finland

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