Publication detail
Deposition of rigid glass fibres inside a replica of female airways
KÁNSKÁ, J. LÍZAL, F. BĚLKA, M.
English title
Deposition of rigid glass fibres inside a replica of female airways
Type
article in a collection out of WoS and Scopus
Language
en
Original abstract
Inhaled fibrous microparticles can pose serious health risks, which have led to significant attention in the last decades. Fibres, particularly the smaller ones, can penetrate deeply into the lungs and reach the alveoli. Their elongated shape causes this. Usual inhalable spherical drugs in the size range of 5 – 10 µm have difficulty reaching the deeper regions of the lung. Thus, the fibrous shape may provide a solution for delivery in these regions, but the mechanics of inhaled fibre flow are more complex compared to spherical particles. Therefore, it is important to understand how specific parameters (e.g. breathing flowrate, dimensions of fibres) influence the flow and deposition of fibrous aerosols in the human airways.
English abstract
Inhaled fibrous microparticles can pose serious health risks, which have led to significant attention in the last decades. Fibres, particularly the smaller ones, can penetrate deeply into the lungs and reach the alveoli. Their elongated shape causes this. Usual inhalable spherical drugs in the size range of 5 – 10 µm have difficulty reaching the deeper regions of the lung. Thus, the fibrous shape may provide a solution for delivery in these regions, but the mechanics of inhaled fibre flow are more complex compared to spherical particles. Therefore, it is important to understand how specific parameters (e.g. breathing flowrate, dimensions of fibres) influence the flow and deposition of fibrous aerosols in the human airways.
Keywords in English
fibres;fibers;glass;female airways;inhalation
Released
11.11.2024
Publisher
Czech Aerosol Society
Location
Milovy - Sněžné
ISBN
978-80-908653-2-7
Book
PROCEEDINGS of the 23rd Annual Conference of the Czech Aerosol Society OVZDUŠÍ V ČASe
Pages count
2
BIBTEX
@inproceedings{BUT196427,
author="Jana {Kánská} and František {Lízal} and Miloslav {Bělka},
title="Deposition of rigid glass fibres inside a replica of female airways",
booktitle="PROCEEDINGS of the 23rd Annual Conference of the Czech Aerosol Society OVZDUŠÍ V ČASe",
year="2024",
month="November",
publisher="Czech Aerosol Society",
address="Milovy - Sněžné",
isbn="978-80-908653-2-7"
}