Detail publikace

Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

LÍZAL, F. ELCNER, J. BĚLKA, M. JEDELSKÝ, J. JÍCHA, M.

Anglický název

Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation

Typ

článek ve sborníku ve WoS nebo Scopus

Jazyk

en

Originální abstrakt

The presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.

Anglický abstrakt

The presence of aerosol deposition hot-spots in human airways presumably contributes to development of various diseases. The overall aerosol deposition in human lungs can be predicted with sufficient accuracy nowadays. However, the prediction of localized aerosol deposition poses arduous challenge, namely in diseased lungs. Numerical simulation is considered to be a promising tool for the successful prediction. Yet, the validation of such simulations is difficult to perform, as not enough experimental data acquired using realistic airway replicas is available. This paper presents a first comparison of localized deposition measurement and simulation performed on the identical realistic geometry. The analysis indicates that both approaches yield similar results for low Reynolds number flows.

Klíčová slova anglicky

aerosol deposition, human lungs, human airways, computational fluid mechanics, experiment

Vydáno

15.11.2016

Nakladatel

EDP Sciences

ISSN

2100-014X

Kniha

EPJ Web of Conferences

Ročník

143

Strany od–do

1–4

Počet stran

4

BIBTEX


@inproceedings{BUT131497,
  author="František {Lízal} and Jakub {Elcner} and Miloslav {Bělka} and Jan {Jedelský} and Miroslav {Jícha},
  title="Prediction of localized aerosol deposition in a realistic replica of human airways using experimental data and numerical simulation",
  booktitle="EPJ Web of Conferences",
  year="2016",
  volume="143",
  month="November",
  pages="1--4",
  publisher="EDP Sciences",
  issn="2100-014X"
}