Detail publikace

MECHANICAL PROPERTIES OF DIFFERENT TISSUES OF CAROTID ATHEROMA: EXPERIMENTAL APPROACH

HRUBANOVÁ, A. BEDNAŘÍK, Z. KUBÍČEK, L. BURŠA, J.

Anglický název

MECHANICAL PROPERTIES OF DIFFERENT TISSUES OF CAROTID ATHEROMA: EXPERIMENTAL APPROACH

Typ

článek ve sborníku mimo WoS a Scopus

Jazyk

en

Originální abstrakt

Atherosclerosis is a life-threatening disease mainly occurring in carotid or coronary arteries. In case of carotid arteries, the rupture of fibrous cap encapsuling the cell debris, also known as lipid core, can induce a stroke. In clinics, the severity of the plaque is assessed only through the size of the stenosis. Computational modelling can help in the decision-making process and can bring deeper insight into the dilemma. The tissues both above the lipid core (referred to as fibrous cap) and beneath it are often not distinguished and specified as “fibrous tissue”. Although some publications suggested that both these tissues have similar mechanical properties [1], others recommend that plaque specific material properties are needed [2]. In this study, the potential difference in mechanical response between fibrous cap and original artery wall (media) is investigated combining histological and mechanical experiments.

Anglický abstrakt

Atherosclerosis is a life-threatening disease mainly occurring in carotid or coronary arteries. In case of carotid arteries, the rupture of fibrous cap encapsuling the cell debris, also known as lipid core, can induce a stroke. In clinics, the severity of the plaque is assessed only through the size of the stenosis. Computational modelling can help in the decision-making process and can bring deeper insight into the dilemma. The tissues both above the lipid core (referred to as fibrous cap) and beneath it are often not distinguished and specified as “fibrous tissue”. Although some publications suggested that both these tissues have similar mechanical properties [1], others recommend that plaque specific material properties are needed [2]. In this study, the potential difference in mechanical response between fibrous cap and original artery wall (media) is investigated combining histological and mechanical experiments.

Klíčová slova anglicky

atherosclerosis; carotid atheroma; experiment

Vydáno

09.07.2023

Místo

Maastricht

Kniha

ESB 2023 BOOK OF ABSTRACTS

Číslo edice

28

Počet stran

1

BIBTEX


@inproceedings{BUT184915,
  author="Anna {Hrubanová} and Zdeněk {Bednařík} and Luboš {Kubíček} and Jiří {Burša},
  title="MECHANICAL PROPERTIES OF DIFFERENT TISSUES OF CAROTID ATHEROMA: EXPERIMENTAL APPROACH",
  booktitle="ESB 2023 BOOK OF ABSTRACTS",
  year="2023",
  month="July",
  address="Maastricht"
}